|
KMID : 0941820210310030198
|
|
Korean Journal of Clinical Pharmacy
2021 Volume.31 No. 3 p.198 ~ p.204
|
|
|
Atherosclerotic Cardiovascular Disease Risk and Statin Prescription Status in Korean Adult Patients
|
|
Kim Jong-Yoon
Rhew Ki-Yon
|
|
|
Abstract
|
|
|
Background: Cardiovascular (CV) disease is known as one of the major causes of death from disease worldwide. Statin therapy playsa pivotal role in atherosclerotic cardiovascular disease (ASCVD) lowering the LDL-cholesterol level effectively. The purpose of thisstudy was to evaluate the association of the intensity of statin therapy in adult patients of Korea and the risk of ASCVD of the patientgroup.
Methods: We used data from sample of patients from the Health Insurance Review and Assessment Service (HIRA-NPS-2018). We analyzed the patterns of prescribing statins including types of statin, statin intensity, and number of patients with ASCVDor risk of ASCVD.
Results: 155,512 patients were included in the analysis, and 27,950 patients (18.0%) was over 75 years. Highintensitystatin usage was increased in ASCVD patients compared with the low-intensity statin use. The OR (odds ratio) of highintensitystatin were increased in myocardial infarction patients compared with low-intensity statin use showing the highest OR;12.40 (95% CI; 9.48-16.22). At patient groups of angina, ischemic heart disease and carotid disease, high-intensity statin prescriptionrate was increased compared with low-intensity statin. However, there was no statistical significance between both statinprescription rates in patients of peripheral arterial disease, abdominal aneurysm, diabetic mellitus and atherosclerosis.
Conclusion:The statin prescription rate showed intensity increasing tendency according to the risk of ASCVD. More aggressive statin therapymight be beneficial for the ASCVD patients based on the recent guidelines of dyslipidemia.
|
|
|
KEYWORD
|
|
|
Statin, intensity, dyslipidemia, ASCVD, atherosclerotic cardiovascular disease
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|